Dec 19, 2023 · In this Review, we first describe the fundamentals of sequencing and computational methods for the generation and analysis of high-dimensional single-cell RNA sequencing data sets.

Jan 1, 2023 · This review demonstrates that single-cell sequencing technology has been widely used in research in regenerative biology and regenerative medicine. Compared to traditional methods, single …

Single-cell RNA sequencing (scRNA-seq) technology has become the state-of-the-art approach for unravelling the heterogeneity and complexity of RNA transcripts within individual cells, as well as …

Researchers from the Lars Bolund Institute of Regenerative Medicine have provided a concise yet insightful overview of single-cell RNA sequencing (scRNA-seq) in a recent review published in …

1 day ago · Conclusions Our study establishes a cost-effective surface marker-based method for deriving transplantable RGC and corneal lineage cells from hiPSCs, overcoming key obstacles in …

Jun 9, 2025 · Here, to address this issue, we induced injury and performed single-cell RNA sequencing on individual cells in skeletal muscle at different time points.

Dec 13, 2025 · Here, we combined single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics to comprehensively profile immune microenvironment changes in the remnant liver during ALPPS. …

Regenerative medicine and tissue engineering aim to promote functional rebuilding of damaged tissue. Comprehensively profiling cell identity, function and..

Jan 10, 2025 · By focusing on single-cell resolution, researchers can uncover novel insights that are often masked by the averaging effects of bulk sequencing, driving advances in fields such as cancer …

Aug 1, 2024 · Regenerative capacities and strategies vary dramatically across animals, as well as between cell types, organs, and with age. In recent years, high-throughput single-cell transcriptomics …