In a recent study posted to the bioRxiv* preprint server, researchers engineered epitope scaffolds (ESs) of conserved regions of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ...
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Massively parallel profiling reveals thousands of hidden viral proteins and conserved mechanisms
Many viruses carry genetic instructions that elude detection by standard genome annotation tools. Beyond the well-documented protein-coding regions, viral genomes often encode noncanonical ORFs, short ...
Researchers comparing the human genome with the genomes of other species have discovered a surprising number of matching DNA sequences in a variety of vertebrate species, including the mouse, rat, dog ...
Researchers from Generate Biomedicines Inc. have detailed the discovery and preclinical characterization of GB-0669, a spike S2-targeted monoclonal antibody (MAb) being developed for the prophylaxis ...
A new LMU study shows how proteins function reliably even without a stable 3D structure—and the crucial importance not only of short sequence motifs, but also of chemical characteristics.
In a recent study posted to the bioRxiv* preprint server, researchers described four novel monoclonal antibodies with potent and broad neutralization activity against severe acute respiratory syndrome ...
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