Chimeric antigen receptor (CAR) T cell-based therapy has greatly improved cancer treatment, especially for hematologic cancers. 1 By providing T cells with synthetic receptors that target tumor ...

Cell migration is a multistep process essential to various physiological functions, including immune cell movement and embryonic development, as well as pathological conditions like tumor metastasis.

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

Discover how specialized cells form immune-boosting niches in lung tumors, unlocking new strategies to enhance cancer treatments and improve outcomes. Study: Fibroblastic reticular cells generate ...

Immune cells are vigilant sentinels stationed at their tissue posts, such as the skin, lungs, or gut, or circulating in the bloodstream. Their presence and ability to quickly mobilize are key defenses ...