Rutgers‑led study of 2.2 million people finds addiction risk is driven more by genes tied to impulse control and reward ...

Most of the genetic risk for developing a substance use disorder comes from genes that broadly affect how our brains process rewards, regulate impulses and weigh consequences—not from genes that ...

Scientists have long known that stress and addiction travel together, but the biological connection between a hard day and a ...

Most of the genetic risk for developing a substance use disorder comes from genes that broadly affect how our brains process rewards, regulate impulses and weigh consequences – not from genes that ...

A large study of data from Veterans Affairs finds that people on GLP-1 drugs were less likely to develop substance abuse disorder or overdose.

The ADHD brain is different, not faulty. The ADHD system can set a person up for addiction. Dopamine levels are the key to ...

-The U.S. opioid crisis has varied in severity across the country, leading to extended debate about how and why it has spread. Now, a study co-authored by MIT economists sheds new light on these ...

Polysubstance use has become a defining feature of the U.S. overdose crisis in the past decade. While not every overdose involves multiple substances, a significant and growing proportion includes ...

Diagnosing substance-use disorder can be difficult because of patient denial related to the stigma attached to addiction. But a new study by the University of Cincinnati uses a novel artificial ...

Researchers have identified the specific number of weekly delta-9-tetrahydrocannabinol (THC) units beyond which the risk for cannabis use disorder (CUD) increases. Using standard THC units — defined ...