Arthur Kornberg compared DNA to a tape recording of instructions that can be copied over and over. How do cells make these near-perfect copies, and does the process ever vary? In reality, the process ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 21 (May 24, 2016), pp. 5916-5921 (6 pages) DNA replication occurs semidiscontinuously due to the ...

The origin of mutations is central to understanding evolution and of key relevance to health. Variation occurs non-randomly across the genome, and mechanisms for this remain to be defined. Here we ...

Undergraduate biology students could be forgiven for thinking that scientists have DNA replication all figured out. After all, textbooks present the models of replication so matter-of-factly that it's ...

DNA replication is a basic function of living organisms, allowing cells to divide and multiply, all while maintaining the genetic code and proper function of the original cell. The process, or ...

As DNA strands ravel and unravel in an intricate dance, one notable event takes center stage: replication. This process is essential to life, but the finer details of its orchestrated steps are still ...

During replication, DNA polymerases are positioned on each strand of DNA . Using a microscope slide as an anchor, we tethered DNA to a bead and stretched it with a flow of solution. We tracked how the ...

Failures in DNA replication can lead to cancer, birth defects or other harm Video shows single pieces of double-helix DNA being copied Single-molecule view gives new insights into this process ...

Accurate transmission of the genetic information requires complete duplication of the chromosomal DNA each cell division cycle. However, the idea that replication forks would form at origins of DNA ...

An enzyme essential for DNA replication and repair in humans works in a way that might be exploited as anti-cancer therapy, say researchers. An enzyme essential for DNA replication and repair in ...

Almost all living creatures, from humans to plants to germs, are created when a single DNA molecule copies itself, continuously repeating our vital genetic data. Now you can see the amazing process ...