Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Salk scientists uncover a key neural circuit in mice that gives pain its emotional punch, opening new doors for treating fibromyalgia, migraine, and PTSD LA JOLLA (July 9, 2025)—Pain isn’t just a ...

A new study has found an old antipsychotic drug blocks a signaling pathway that has been linked to chronic neuropathic pain. The surprising findings not only point to novel future treatments for pain ...

Scientists have uncovered a link between chronic pain and lung cancer—a link that also offers a potentially druggable pathway for both conditions, according to new research conducted in mouse models.

Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top) by ...