Indiana University School of Medicine scientists have developed a powerful new imaging technique to study bone marrow in mouse models. By overcoming key challenges unique to imaging this complex ...

Cell- and animal-based models of bone formation reveal novel mechanisms involved in the cartilage-to-bone phenotype ...

Bone marrow contains stem cells that make the many types of blood cell our immune system needs. The diversity of these blood cells drops as we age, and this is thought to contribute to some aspects of ...

Single-cell transcriptomics data from mouse bone-relevant cells was used to inform human bone mineral density genome-wide association studies and prioritize genetic targets with potential causal roles ...

In a recent study published in the journal Nature, a group of researchers revealed hierarchical stem-cell arrangements in bone marrow (BM) niches that govern regeneration, immune privilege, and ...

Scientists from Cincinnati Children’s Hospital Medical Center, Massachusetts General Hospital, and elsewhere have been able to pinpoint cells in mouse bone marrow that give rise to specific types of ...

Imagine being able to count the different types of blood cells being formed inside the tiny bones of a mouse and pinpointing the strings and clusters of cells within the bone marrow that are ...

Stem cells form the backbone of many cell-based therapies due to their unique properties, including the ability to self-renew and differentiate to many cell types. Multiple cell therapies deliver ...

Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each day to keep the oxygen flowing. For many years, ...