Light microscopy is a cornerstone in life sciences technology, having experienced considerable diversification since its inception. This development becomes visible when considering the distinctive ...

Light microscopy is one of the most essential technologies in life science research. Advances in optoelectronic detectors and the widespread availability of laser-based light sources have led to the ...

Light-sheet microscopy is a rapidly developing field thanks to the numerous benefits and vast number of implementations when imaging with a light sheet. However, these benefits are best realized when ...

descSPIM enables three-dimensional imaging of diverse tissues like neural cells and cancerous tumors. The widespread dissemination and adoption of descSPIM can accelerate biomedical discoveries. Three ...

The ability to image biological samples with a high spatio-temporal resolution is becoming increasingly important in biological and medical applications. In such applications, light sheet microscopy, ...

Researchers have incorporated a swept illumination source into an open-top light-sheet microscope to enable improved optical sectioning over a larger area of view. The advance makes the technique more ...

The Advanced Light Microscopy and Innovation Lab (ALMIL) supports MSK researchers by advancing the use of cutting-edge imaging techniques to study complex biological systems. As a specialized hub, ...

Light-sheet microscopy (LSM) techniques are designed to illuminate thin slices of a larger sample with perpendicular laser illumination, as a way to improve signal-to-noise performance and reduce ...

SLICE addresses one of the most significant challenges in modern biological research: the limited accessibility of high-performance light sheet microscopy due to high costs and complex infrastructure ...

The brain is the most energy-demanding organ in the body, in part due to its complexity. Its components are varied and intricate: comprising different cell types, including neurons designed to ...

A team of researchers has developed an innovative imaging platform that promises to improve our understanding of cellular structures at the nanoscale. This platform, called soTILT3D for ...