Free radical chemistry centres on the study of species that possess one or more unpaired electrons – a feature that confers unique reactivity and diverse roles across chemical and biological systems.

The removal of carboxyl groups and the release of alkyl radical fragments from the tight binding of carboxyl groups are promising directions in organic synthesis, especially in drug synthesis. Various ...

Boston College team reports new catalytic process allows for selective transformation of the carbon-hydrogen bonds in common alkenes into value-added new alkenes bearing useful amine functionalities ...

One of the central challenges for synthetic chemists is to impose control over free radicals. Highly reactive molecules with an unpaired electron, free radicals may be familiar to you; these are the ...

Making molecules with quaternary carbon bonds—four carbons attached to a central C—is tricky but necessary for medicinal chemists. Quaternary C bonds have a discrete shape, Princeton University ...

Nitrogen rings with attached chiral organic groups are common motifs in pharmaceuticals, agricultural chemicals, and bioactive small molecules. Medicinal chemists frequently seek to add chemical ...

Free radicals steal charged particles from healthy cells, causing damage. Antioxidants can neutralise their effects, reducing ...