A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

image: Enzyme substrate specificity involving material conversion processes is pertinent to e.g. biochemistry, metabolic engineering, and environmental remediation; however, it is one of the most ...

Nitrilases are a unique class of enzymes that catalyse the hydrolysis of nitrile compounds to yield the corresponding carboxylic acids or amides. Their application in biotransformation processes has ...

PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, perspectives, reviews, colloquium papers, and actions of the Academy. In ...

Enzymes are biological catalysts that speed up chemical reactions in living organisms. They are essential for life, as they play a crucial role in various biological processes, such as digestion, ...

Researchers have unveiled the crystal structures of UBA6 in complex with either ATP or the ubiquitin-like protein FAT10. These results provide the foundation to study the individual roles of UBA6 ...

A University of North Florida biology professor has been awarded a prestigious four-year National Institutes of Health (NIH) grant totaling over $720K to study the functional role of an enzyme called ...

In a new study published in Nature titled, “Custom CRISPR-Cas9 PAM variants via scalable engineering and machine learning,” researchers from Massachusetts General Hospital (MGH) and Harvard Medical ...

Researchers from the University of Massachusetts, Amherst, say they have made an important discovery on how cells handle stress. Using bacterial cells, the team found that a damage-repairing enzyme, ...