Cataplexy, or sudden muscle weakness that can resemble fainting, may be prompted by strong emotions. This symptom isn't serious and mostly occurs with narcolepsy type one — otherwise, it's very rare.

Narcolepsy with cataplexy, now known as type 1 narcolepsy, is a chronic neurological disorder that affects a person’s sleep-wake cycle and involves muscle weakness. The condition can cause a person to ...

Cataplexy is a sudden episode of muscle weakness that occurs while fully aware and conscious. It can be triggered by emotional events, such as laughing, crying or fear, and is usually transient in ...

Pitolisant (Wakix) in children ages 6 years and up led to clinically meaningful improvements in narcolepsy symptoms in a phase III trial. Among 110 kids with narcolepsy with or without cataplexy, ...

Pitolisant is now the only treatment option not scheduled as a controlled substance that is indicated for both excessive daytime sleepiness and cataplexy in pediatric and adult patients. The Food and ...

An investigational oral selective orexin receptor 2 agonist (oveporexton, Takeda) demonstrated significantly improved measures of wakefulness, sleepiness, and cataplexy in a phase 2b study of adults ...

And not figuratively, either. Sometimes people have found that certain emotions literally cause their muscles to unhook from their brains. They collapse entirely. This is not some strange disease, or ...

Narcolepsy is a sleep disorder that causes abnormal sleep and wake cycles. It often shows up as an excessive and irresistible urge to sleep during the day, along with restless or disrupted sleep at ...

Please provide your email address to receive an email when new articles are posted on . Lumryz is an extended-release, once-at-bedtime oral suspension for cataplexy or excessive daytime sleepiness in ...

Orexins are neurotransmitters, which are chemicals in your brain that send messages from one neuron (a nerve cell) to another. When you’re awake, those neurons send out orexins. The orexins then bind ...