A 75-year-old woman with osteoporosis presented with a 2-year history of anterior thigh pain that was worse when standing and walking. She had taken alendronate for more than 20 years, which was ...

Please provide your email address to receive an email when new articles are posted on . TORONTO — New data reveal an association between oral bisphosphonate use and atypical subtrochanteric femoral ...

Long-term bisphosphonate therapy can change bones at the microscopic level to make them more susceptible to the rare catastrophic transverse breaks known as atypical femoral fractures (AFFs), ...

Please provide your email address to receive an email when new articles are posted on . “Although rare, the effect of a painful, spontaneous atypical femur fracture is devastating,” Hanh H. Nguyen, ...

The authors of the study analyzed 166 femur fractures in 119 children with OI Data from a retrospective study of children with osteogenesis imperfecta (OI) suggests that atypical femur fractures are ...

May 25, 2012 — The incidence of atypical femur fractures has increased during the past decade, and this increased risk is associated with bisphosphonate use, according to a recent study published ...

A new position paper on "atypical" subtrochanteric fractures in association with long-term treatment with bisphosphonates examines available evidence which indicates that the proven benefits of ...

Bisphosphonates have been linked to increased risk for atypical femoral fractures (AFFs), but the usual definition of AFF excludes periprosthetic femoral fractures (PFFs) in patients with hip or knee ...

The relative risk of an atypical femoral fracture with bisphosphonate use related to duration of therapy, with the highest risks being seen after 5 years of exposure, a nationwide study in Denmark ...

Since 2007, there have been several reports suggesting a potential association between the use of bisphosphonates and the occurrence of subtrochanteric or so-called atypical femoral fracture. 1–4 ...

Epidemiologic studies and case series and reports suggest that there is a relation between the long-term use of bisphosphonates and the development of atypical femoral fractures. 1 Although the cause ...