It is widely recognized that the Barbier–Grignard-type reaction is one of the most important methods for forming carbon–carbon bonds and has widespread synthetic applications in modern organic ...

The importance of aryl sulfides in biologically active compounds has led chemists to develop methods to synthesize them from carbon-sulfur bond forming reactions. The conventional reaction, however, ...

Palladium catalysts help synthesize key chemicals for many industries. However, direct reaction of two basic reagents, aryl halides and alkyllithium compounds, remains a challenge. Now, a team of ...

In recent years, transition-metal-catalyzed carbon-carbon bond-forming chemistries have become essential tools for the development of agrochemical and pharmaceutical active ingredients and other fine ...

Biochemists may soon find themselves reaching for palladium reagents—chemicals once thought to be exclusively used in organic synthesis—to couple small molecules, such as drugs, onto proteins.